A heavy traffic jam is expected along Mombasa Road as the busy highway will be closed today (Tuesday) at Taru area.
The closure is meant to allow for the erection of a Standard Guage Railway overpass at Taru.
China Road and Bridge Corporation (CRBC) in a Monday advert in local dailies cautioned motorists to use alternative routes to and from the Central Business District.
The closure will last for twelve hours- from 6am to 6pm.
The company said police will be deployed along the road to help control traffic.
CRBC is currently constructing a modern railway line from Mombasa to Nairobi.
The second phase of the Sh380 billion investment will stretch from Nairobi to Kisumu according to Transport Cabinet Secretary James Macharia.