[President Uhuru Kenyatta with Dlamini Zuma in a past event. She lost her bid to become ANC President. Photo/Nation]

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Dlamini Zuma, a former chair to African Union Commission, suffered defeat in her quest to lead South Africa's iconic party, ANC, reports the BBC.

Zuma, who played integral role in acquittal of President Uhuru Kenyatta and his Deputy William Ruto, lost to incumbent Deputy President Cyril Ramaphosa.

Coincidentally, Ramaphosa is a close confidant to Raila Odinga, Kenya's celebrated politician, who is a perennial rival of President Kenyatta.

Moments after the victory of Kenyatta in 2013, Ms Zuma, an Ex-wife to President Jacob Juma, led a spirited campaign at the global court, ICC that demanded Uhuru to be given a 'break' following an attack at Westgate Mall.

What followed was a series of campaigns targeting withdrawal of African States from The Hague based court, a campaign that was led by the former South African Foreign Minister.

In one of press conferences, ICC prosecutor Fatou Bensouda, accused Zuma of 'sabotage' in Kenyan cases according to the Daily Telegraph.

So close that they are, Zuma and Kenyatta have been photographed in a number of African Union functions with the latest being in January 2017 when her term elapsed.

Following massive campaigns under Zuma's leadership, Uhuru's case was withdrawn for lack of 'sufficient' evidence, moments after making history for being the first sitting president to attend trials.

But in South Africa, her dreams to lead one of Africa's most advanced economy were thwarted after losing to Ramaphosa, who garnered 2440 votes to Zuma's 2261.

While winning ANC presidency is not a guarantee of becoming president, it however puts one in pole position given all presidents have always come from the independence party.

Senate Majority Leader Kipchumba Murkomen said: "Congratulations Dlamini for putting a spirited fight."

Raila Odinga's close confident and Naorok Senator Ledama Ole Kina said: "It started in Harare and now in South Africa. Uhuru Kenyatta be ready, you're next."